Description: B6, zinc and magnesium are critical for numerous reactions that occur in the body. Lacking any of these critical nutrients can have far reaching consequences. Deficiency of B6 is not uncommon due to poor diet, depleting medications, excessive alcohol intake and parasitic infections. Deficiency symptoms include dermatitis, cracked and sore lips, inflamed tongue and mouth, neuropathy, confusion, and insomnia.
B6 serves as a coenzyme to four classes of enzymes. It combines with an alpha-amino acid to form a compound called a Schiff base, which is the substrate in four kinds of reactions: transamination (movement of amino groups), racemization (redistribution of enantiomers), decarboxylation (removing COOH groups), and various side-chain reactions depending on the enzyme involved. Vitamin B6, also called pyridoxine, is one of eight water-soluble B vitamins. Vitamin B6 is involved in the metabolism of protein and carbohydrates, the production of insulin and red and white blood cells, and the synthesis of neurotransmitters, enzymes, and prostaglandins. Vitamin B6 is essential in numerous biochemical pathways involving red blood cells, the immune system, central nervous system function, protein metabolism, homocysteine metabolism, and also the production of energy. Pyridoxine is an especially important vitamin for maintaining healthy nerve and muscle cells and it aids in the production of DNA and RNA, the body's genetic material. The human body needs vitamin B6 to make hemoglobin. Hemoglobin within red blood cells carries oxygen to tissues. Vitamin B6 also helps increase the amount of oxygen carried by hemoglobin. A vitamin B6 deficiency can result in a form of anemia that is similar to iron deficiency anemia. B6 is needed to make sphingomyelin and other sphingolipids and is also necessary for proper absorption of vitamin B12.
B6 (50-200 mg) May Help Support:
Carpal Tunnel Syndrome, PMS, Menopause, Fatigue, Copper Toxicity, High Histamine, Pyroluria, Depression, High Homocysteine, Sideroblastic anemia, Cheilosis, Seborrhoeic dermatitis, MSG sensitivity, ADHD.
The Immune System and B6-Calories, protein, vitamins, and minerals are all important to the immune system because they promote the growth of white blood cells that directly fight infections. Because of its involvement in protein metabolism and cellular growth, vitamin B6 is very important to the immune system. It helps maintain the health of lymphoid organs (thymus, spleen, and lymph nodes) that make our white blood cells. Animal studies show that a vitamin B6 deficiency can decrease antibody production and suppress the immune response.
Depression, Moods and B6-B vitamins are often used to improve symptoms of depression. Associated symptoms of depression often include fatigue, sleep disturbances, loss of interest or pleasure in most activities, changes in appetite and headaches. Also associated with depression are imbalances in neurotransmitter production and/or essential fatty acids. Designs for Health's Comprehensive Metabolic Profile (CMP) evaluates patients' levels of the important fatty acids: EPA, DHA, GLA, AA as well as serotonin production and the catecholamines epinephrine (adrenaline) and norepinephrine (noradrenaline). Over-production of catecholamines can lead to anxiety and panic attacks, both of which are growing in number of incidence in young people today. Vitamin B6 is a key player in the metabolism of neurotransmitters. For example, it is needed to convert 5- hydroxy-tryptophan (5-HTP) into serotonin (5-HT) and is needed for converting L-Dopa to Dopamine. It also is needed for the conversion of tryptophan into niacin. The forming of histamine, adrenaline (norepinephrine) and GABA are also dependent on vitamin B6. One particular study of 11 hyperactive children found them to be particularly low in serotonin. When they were given B6, serotonin levels improved as well as B6 levels in the blood. Research demonstrates that B6 down-regulates glucocorticoid receptors and in turn calms down the sympathetic response to stress.
Key Ingredients: Magnesium-Magnesium is an essential mineral nutrient and is present in every cell type in every organism. Magnesium dependent enzymes appear in virtually every metabolic pathway. Magnesium is used as a signaling molecule, and much of nucleic acid biochemistry requires magnesium, including all reactions which require release of energy from ATP. Many disease states are
associated with low magnesium levels including diabetes, fibromyalgia, chronic fatigue syndrome, and congestive heart failure. CMP testing can show insufficient needs being met for magnesium. The magnesium bisglycinate chelate used in Sublingual B6 meets the NNFA definition of a true mineral chelate.
Zinc-Zinc supplementation is often used to rid excess copper from body tissues. Zinc is needed for proper functioning of over 40 enzymes in the body. For example, it is needed for the action of the delta 6 desaturase enzyme involved in fatty acid conversions. Deficiency of zinc can lead to an elevated ratio of linoleic to dihomogammalinoleic acids (LA/DGLA). This can be detected and corrected with the Comprehensive Metabolic Profile (CMP). Designs for Health's Zinc Challenge is excellent for detecting zinc deficiency and for quick assessment of efficacy of dosing. Low zinc levels can lead to problems with appetite control, sense of taste and smell, ability to fight infections and protein utilization. Zinc supplementation is also often used to rid excess copper from body tissues. Zinc bis-glycinate chelate used in Sublingual B6 meets the NNFA definition of a true mineral chelate.
Suggested Use: One teaspoon daily or as recommended by your health care professional.
Contraindications: If you are pregnant or nursing, consult your physician before taking this product.